A visit to a natural history museum proves catastrophic for two high school rivals, an overachiever and a jock, when an ancient Aztec statue casts a spell that causes them to switch bodies and see exactly what it's like to walk in the other's shoes.
Cliff receives an unusual 18th birthday gift from his younger sister — marijuana, alcohol, a subway token and the mission to lose his virginity. This results in Cliff meeting a young street hustler named Butch. At first, as Butch introduces Cliff to gay street life in Toronto, Cliff is excited by his new relationship. But as the two grow closer, he finds that Butch has problems, including drug addiction, that are cause for serious concern.
In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.
A popular TV sitcom actress struggles with her drug and alcohol-addled private life while her manager does "damage control" for her own protection from the press, which is becoming increasingly difficult.
An Arctic oil rig crew discovers something strange far beneath the Earth's surface, which may or may not be responsible for the series of murders that begin to take place.
A game designer on the run from assassins must play her latest virtual reality creation with a marketing trainee to determine if the game has been damaged.