This is the story of a vagrant samurai – the solitary, savage and scrupulous Kiba – who arrives at a village to defend a beautiful, blind woman against a sinister plot. Her assailants then send against him another samurai, named Sana, who is without scruples. The fight between them will become personal, for the honor and love of the blind woman.
In Osaka during the Edo period, ruler Sanada Yukimura was in losing position, fearing Toyotomi's blood descendents would end, he impregnates one of five Shinano female ninja with the seed of Toyotomi Hideyoshi in hopes of continuing the bloodline. Princess Sen and the five female ninja escape from Osaka castle by blending in with the handmaidens. Lord Tokugawa Ieyasu who was supposed to rule all under the heavens was informed of this secret. So Ieyasu orders five samurai of the Iga Ninja clan (brought by Hattori Hanzo) to stop the Toyotomi bloodline by killing the Kunoichi ninja. An attack of ninja magic arts unfolds in a battle of the sexes.
