Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.
Workaholic Jim Evers and his wife/business partner Sara get a call one night from a mansion owner, Edward Gracey, who wants to sell his house. Once the Evers family arrive at the mansion, a torrential thunderstorm of mysterious origin strands them with the brooding, eccentric Gracey, his mysterious butler, and a variety of residents both seen and unseen.
