One hundred years after a nuclear war has devastated the planet, society has been reborn into two factions; the underground society and the scavangers above in the wastelands. A group of scavangers on bikes come across a town infested with flesh eating rats, and soon the gore is spilling everywhere.
A priest-doctor chasing a man with supernatural regenerative abilities, who has recently escaped from a medical lab, reaches a small town where the mutant goes on a killing spree.
A pair of smugglers manage to pick up a castaway while running from the authorities, who turns out to be the only survivor from a secret mission to destroy a mysterious superweapon designed by the evil Count Zartharn. The smugglers are soon recruited by the Emperor to complete the mission, as well as to rescue the Emperor's son, who has gone missing.
While doing undercover work in a mental hospital, Emanuelle discovers a girl who seems to have been raised by a tribe of amazonian cannibals. Intrigued, Emanuelle and friends travel deep into the Amazon jungle, where they find that the supposedly extinct tribe of cannibals is still very much alive.