Fifteen years after the original film, the philosophical Lieutenant William F. Kinderman is investigating a baffling series of murders on Georgetown that all contain the hallmarks of The Gemini, a deceased serial killer. His investigation eventually leads him to a catatonic patient in a psychiatric hospital who has recently started to speak, claiming he is The Gemini and detailing the murders, but bears a striking resemblance to Father Damien Karras.
Julius Orlovsky, after spending years in a New York mental hospital, emerges catatonic and must rely on his brother Peter, who lives with poet Allen Ginsberg. When Julius wanders off in the middle of filming, Frank hires and actor (Joseph Chaikin) to play the character and begins a fictional version of his psychological portrait. Then, as suddenly as he vanished, Julius turns up in an institution where he and Peter must face their relationship.
Coogan, an Arizona deputy sheriff goes to New York to pick up a prisoner. While escorting the prisoner to the airport, he escapes and Coogan heads into the city to recapture him.
Jean Wells (Dierking) believes she kills a man during a hit-and-run one evening. A man named Joe (Saegers)appears and, in exchange for keeping silent about the murder, blackmails Wells. Wells begins to doubt the accident and struggles with her sanity.