65 year old doctor Pierfrancesco works as a night-shift medical guard. He’s a grumpy man, full of aches and pains and is very rough with his patients. One night, he’s involved in a road collision with 30 year old delivery man Mario. While uninjured, Mario's bicycle is destroyed, and Pierfrancesco's sciatica flares up, making it impossible for him to drive. With both of their jobs in jeopardy, the doctor has an idea that could help them both: “remotely guided” by Pierfrancesco via wireless headset, Mario will visit his patients, and they’ll also carry out Mario’s delivery in Pierfrancesco’s car. After a range of daring (mis)adventures, they will learn to support each other, and the night will end with their lives both changed for the better.
Ulisse, Fulvio and Domenico decide to rent an apartment together in order to live with their modest work. However the three encounter any difficulties that have forced them to always be one step away from starvation. Ulisse has to maintain his wife and daughter selling recordings of important foreign singers, Fulvio has the task of reviewing silly scandals of celebrities instead of writing articles for major artists, while Domenico must keep his wife and children going to make love with old single pensioners.
