The Caribbean Mystery is a remake of Mr. Moto on Danger Island (1939)-which in turn was a remake of Murder in Trinidad. James Dunn stars as Mr. Smith, a Columbo-like Brooklyn detective who pops up on a tropical island to track down some missing geologists.
David Huxley is waiting to get a bone he needs for his museum collection. Through a series of strange circumstances, he meets Susan Vance, and the duo have a series of misadventures which include a leopard called Baby.