A rare mutation has occurred within the vampire community - The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves. Blade is asked by the Vampire Nation for his help in preventing a nightmare plague that would wipe out both humans and vampires.
American Police officer Jack Hazard heads for South America after being ordered to take time off by his boss after a raid goes bad. Once there, however, he finds himself caught up with a stranger wanted by the government, and soon ends up in prison. He and his unwanted companion escape, and now Jack must try to get back to safety while being hunted down by an iron-fisted tyrant.
