An ex-soldier, a teen and a cop collide in New Orleans as they hunt for the source behind a dangerous new pill that grants users temporary superpowers.
Jane, a struggling but perpetually stoned actress, has a busy day ahead. She has several important tasks on her list, including buying more marijuana. Even though she already has a good start on the day's planned drug use, she eats her roommate's pot-laced cupcakes and embarks on a series of misadventures all over Los Angeles.
Biker Cary Ford is framed by an old rival and biker gang leader for the murder of another gang member who happens to be the brother of Trey, leader of the most feared biker gang in the country. Ford is now on the run trying to clear his name from the murder with Trey and his gang looking for his blood.
The Herlihys are a working class family from Chicago whose three children take wildly divergent paths: Brian joins the Marines right out of High School and goes to Vietnam, Michael becomes involved in the civil rights movement and after campaigning for Bobby Kennedy and Eugene McCarthy becomes involved in radical politics, and Katie gets pregnant, moves to San Francisco and joins a hippie commune. Meanwhile, the Taylors are an African-American family living in the deep South. When Willie Taylor, a minister and civil rights organizer, is shot to death, his son Emmet moves to the city and eventually joins the Black Panthers, serving as a bodyguard for Fred Hampton.