The UFC celebrated its 25th Anniversary at this event, given its first event took place on November 12, 1993. This event also took place in the same city as the inaugural show. A featherweight bout between former UFC Lightweight Champion Frankie Edgar and former UFC Featherweight Championship challenger Chan Sung Jung was expected to serve as the event headliner. However on October 26, it was reported that Edgar pulled out due to injury and was replaced by The Ultimate Fighter: Latin America featherweight winner Yair Rodríguez. A lightweight bout between Beneil Dariush and Chris Gruetzemacher was expected to take place at the event. However on October 19, it was reported Gruetzemacher withdrew from the event due to undisclosed reasons and was replaced by promotional newcomer Thiago Moisés. At the weigh-ins, former UFC Women's Bantamweight Championship challenger Raquel Pennington weighed in at 138 lbs, 2 pounds over the bantamweight non-title fight limit of 136 lbs.
UFC 224: Nunes vs. Pennington is a mixed martial arts event produced by the Ultimate Fighting Championship held on May 12, 2018, at the Jeunesse Arena in Rio de Janeiro, Brazil.
UFC 218: Holloway vs. Aldo 2 is a mixed martial arts event produced by the Ultimate Fighting Championship held on December 2, 2017 in Detroit, Michigan.
UFC 209: Woodley vs. Thompson 2 is a mixed martial arts event produced by the Ultimate Fighting Championship held on March 4, 2017 at the T-Mobile Arena in Paradise, Nevada.
UFC Fight Night 99: Mousasi vs. Hall 2 (also known as UFC Fight Night 99) is a mixed martial arts event held by the Ultimate Fighting Championship on November 19, 2016 at The SSE Arena in Belfast, Northern Ireland.
The Ultimate Fighter: Team Joanna vs. Team Cláudia Finale (also known as The Ultimate Fighter 23 Finale) was a mixed martial arts event held on July 8, 2016 at the MGM Grand Garden Arena in Las Vegas, Nevada. This event was a part of UFC International Fight Week.
