Ebisuzawa Kurumi, Takeya Yuki, Wakasa Yuri, and Naoki Miki all attend the same high school. They also live on campus at the school. The girls enjoy their time at the school until students become infected by a virus and turn into zombies. The girls are surrounded by student zombies and they struggle desperately to survive.
Following the events of Ju-on: The Beginning of the End, Mai, the older sister of elementary schoolteacher Yui Shono, goes to look for her sister, who disappeared after a year while working in an elementary school. Mai soon discovers the Teriyaki household who tells her about what happened to her sister. Mai will now uncover the dark secrets of Ju-on and will try to end the curse once and for all.
