Pepe is a 12-year-old boy who lives with his grandmother, a witch-businesswoman. After discovering that he is adopted and that his parents are alive, he decides to go in search of them, but thus ends up attracting the attention of Edmundo, a biomechanical villain who needs Pepe to realize his enormous evil plan: use the boy's energy to conquer the immortality of its kind.
When a spaceship crashes to Earth and reveals a group of quirky little space aliens on the run for their lives, the "GadgetGang" kids-Gus, Phoebe, Francesco, Mitsue, Mary Ann, Banana and Tank-soon discover this won't be the boring weekend they had expected. They soon learn that in a point far from the galaxy, an evil warlord named Gana Golber has seized control of the Confederation of Planets and now all of the planets are in danger-including Earth!
