Students from five different countries arrive in Maruko's town. Maruko and her classmates can barely contain their curiosity, and their new friends are full of surprises. And Maruko's family will house a boy from Italy!
The search for documentation about the sea for a school work will make the magic door of Doraemon open and take Nobita to Shizuka, Gian and Sueno in the deep ocean. This time our friends embark on a huge and unique boat in order to learn about the mysteries of the sea and look for treasures. What nobody imagines is that a distortion in the line of space-time will lead them to the seventeenth century amid a great storm that will make them wreck and where Doraemon loses its magic pocket. No time to lose, our friends must find a way out. Will they succeed?
The hero Nike and magic user Kukuri learn of the "Pickle of Happiness", an item that will grant a wish to the one who eats it. With the help of old friends, they must beat the monsters to the Pickle and convince its guardian dragon to give it to them.
Chibi Maruko chan is the nickname of a sweetly obnoxious 9-year-old girl. She tricks her grandfather, ponders for hours over how to spend her allowance, and hates sitting next to ugly boys. She talks, feels and lives just as real kids do. As the second term commences, Maruko and her classmates return to their small groups. Maruko’s group includes two naughty boys and Maruko is forced to be one of their subordinates. She seems to face a lot of pressure at school.
Ryuuichi is a high-school student tired of living in a small town with small people. He's determined to claw his way to the top of Tokyo, and he'll use any woman he can to do it.
Son of a viscount and a Roma prostitute (both deceased), Serge is intelligent, sweet, talented, and alienated by his family due to his heritage. Upon being sent to his new school, he rooms with Gilbert Cocteau, a gorgeous loner of a boy who sells his body for reasons unknown. Serge's attempts to reach out to Gilbert fail spectacularly, and yet there is something in both of them that attracts them to each other.
The mythical eight-headed serpent Orochi was created by aliens, which invaded Earth in ancient times. 2000 years later, they dispatch the Orochi again to destroy Japan and the rest of the world. Only a team of the Japan Self-Defense Forces and a scientist can destroy it.