John Quincy Archibald is a father and husband whose son is diagnosed with an enlarged heart and then finds out he cannot receive a transplant because HMO insurance will not cover it. Therefore, he decides to take a hospital full of patients hostage until the hospital puts his son's name on the donor's list.
Jonas Ambler is a rich businessman whose wife is killed by kidnappers, so he decides to get even. He hires a mercenary to find and kill the kidnappers. There's only one catch --- he wants to go with them.
On their way home from Brooklyn, psychiatrist Vic, daughter Julie and sister Stacey run short of gas. They leave the highway to search for a petrol station - but end up erring around in South Bronx. A youth gang led by the sadistic Ice stops their car and starts terrorizing them. Without fuel, the 3 women soon have to flee by foot and defend their life with all means possible.
