A serpentine day in the life of ten seemingly disparate women: a porn star, a flight attendant, a psychiatrist, a masseuse, a bartender, a pair of call girls, etc. All of them with one crucial thing in common. Trouble.
A reporter on the trail of a sinister cult wakes up in a morgue to find herself a member of the undead. She goes on a personal vendetta for a group a cultists that are responsible for her death.
Brad, an art student hoping to win a prestigious fellowship, finds his life and career turned upside down when he falls for a faculty member at his college, Lisa Ducharme, who just happens to be his girlfriend's thesis adviser...
The story follows the two sisters Melissa and Emily, the former who accidentally killed her husband Alan and the latter who agrees to help her bury her husband in the desert. While there, they encounter a trucker who hates his dogs and takes a special dislike to the sisters, a Park Ranger who takes a shine to Melissa and finally a strange, homeless man who thinks he is in a soap opera. While Melissa and Emily try their best to find a suitable place to bury Alan, much of their history is revealed and the day in the desert has a great impact on their lives.
After being falsely accused of stealing the budget for their annual cocktail cruise, three very different fraternity brothers are kicked out of their dorm. In order to clear their name and to secure their future careers, the three dress up in drag and pledge the sorority next door where they learn a few valuable - and hilarious - lessons about themselves and the female species.