Maquia is a member of a special race called the Iorph who can live for hundreds of years. However, Maquia has always felt lonely despite being surrounded by her people, as she was orphaned from a young age. She daydreams about the outside world, but dares not travel from her home due to the warnings of the clan's chief. One day the kingdom of Mezarte invades her homeland. They already have what is left of the giant dragons, the Renato, under their control, and now their king wishes to add the immortality to his bloodline. They ravage the Iorph homeland and kill most of its inhabitants. Caught in the midst of the attack, Maquia is carried off by one of the Renato. It soon dies, and she is left deserted in a forest, now truly alone save for the cries of a single baby off in the distance. Maquia finds the baby in a destroyed village and decides to raise him as her own, naming him Ariel. Although she knows nothing of the human world, how to raise a child that ages much faster than her.
A mysterious virus, nicknamed Medusa, is spreading around Japan, turning its victims into stone. Given the impossibility of finding an immediate cure, the government opts for cryopreserving a select group of patients until they come up with a solution. Kasumi, one of the chosen ones, has been asleep for years and her awakening, more than a bed of roses, is a bed of thorns, and happens in the midst of total chaos where monstrous creatures lie in wait all around.
Pen-Pen, the hat-and-tie-wearing prince of Penguin Land, turns up unexpectedly on little Mika's doorstep. and invites himself and his zany friends to stay.
