When Alita awakens with no memory of who she is in a future world she does not recognize, she is taken in by Ido, a compassionate doctor who realizes that somewhere in this abandoned cyborg shell is the heart and soul of a young woman with an extraordinary past.
In the near future where humanoid robots are common in society, the mob reprograms a female android to think and feel in order to use it as a contract killer. This has dangerous consequences as she develops a relationship with her creator while also slowly becoming a murderous psychopath.