Blonde Betty Elms has only just arrived in Hollywood to become a movie star when she meets an enigmatic brunette with amnesia. Meanwhile, as the two set off to solve the second woman's identity, filmmaker Adam Kesher runs into ominous trouble while casting his latest project.
Initially, "Mulholland Dr." was to mark David Lynch's return to television. It is a retooling of a script originally shot as a 94-minute pilot for a TV series (co-written with TV screenwriter Joyce Eliason) for the channel ABC, which had approved the script, but chose not even to air the pilot once it was done in 1999, despite Lynch's labours to cut the project to their liking. It was left in limbo until 18 month later French company Studio Canal Plus (also producer of 'The Straight Story') agreed to pay ABC $7 million for the pilot, and budget a few million more to turn the pilot into a two-hour, 27-minute movie. The cost of the film doubled to $14 million as sets had to be reconstructed and actors recalled.
Daryl Zero is a private investigator and—along with his assistant, Steve Arlo—he solves impossible crimes and puzzles. Although Daryl's a master investigator, he doesn't know what to do with himself when he's not working; he has no social skills, writes bad music and drives Steve crazy.
Aspiring architect Tom Thompson is told by mysterious Ruth Abernathy that his best friend, "Bill," has taken his own life. Except that Tom has never met Bill and neither have his incredulous friends. So when Tom foolishly agrees to give the eulogy at Bill's funeral, it sets him on a collision course with Ruth -- who is revealed to be Bill's oversexed mother -- and Julie DeMarco, the longtime crush Tom hasn't seen since they were teens.
Rusty Sabich is a deputy prosecutor engaged in an obsessive affair with a coworker who is murdered. Soon after, he's accused of the crime. And his fight to clear his name becomes a whirlpool of lies and hidden passions.
Basket-case network news producer Jane Craig falls for new reporter Tom Grunnick, a pretty boy who represents the trend towards entertainment news she despises. Aaron Altman, a talented but plain correspondent, carries an unrequited torch for Jane. Sparks fly between the three as the network prepares for big changes, and both the news and Jane must decide between style and substance.
At Kudzu County's annual Harvest Festival, a virgin must be sacrificed, to keep the giant kudzu vines from destroying the town, but plans go awry when a talk-show host from out of town gets involved.