Weezy (Louise) is a cerebral thirty-something soon to be married and unable to feel anything more than just fine about that. Weezy's girlfriends throw her an unwelcome bachelorette party but the night ends up taking a very unlikely turn when Weez makes a connection with Edie, an out-of-town visitor who manages to crash the celebration. The party goes way off course, taking Weez's sense of self with it...
Jefferson is a lovable ski-bum temp worker whose singular joy comes from an annual excursion to the slopes with fellow vagabond/best friend, Curtis. When Jefferson falls for fellow temp worker, Stephanie, an ambitious go-getter, he is forced to re-evaluate his minimum wage, minimum commitment lifestyle.
Reeling from withdrawal effects after a pharmaceutical drug trial, a reclusive aspiring illustrator sets out to form a relationship with an outgoing gal despite his continuous efforts at solitude and isolation. Parker is uncertain if he suffers from anxiety, but as the medication leaves his system he can barely perform daily tasks. Struggling with withdrawals and anxiety following a pharmaceutical research study, Parker wants nothing but to be left alone. Following a chance encounter with Teresa, a young woman with whom he previously crossed paths, he attempts a step in the opposite direction.
For Nick, Kurt and Dale, the only thing that would make the daily grind more tolerable would be to grind their intolerable bosses into dust. Quitting is not an option, so, with the benefit of a few-too-many drinks and some dubious advice from a hustling ex-con, the three friends devise a convoluted and seemingly foolproof plan to rid themselves of their respective employers... permanently.