Nadie ama a nadie por más de dos años" es una adaptación de la obra de Nelson Rodrigues sobre cinco parejas que viven en Brasil a principios de los años 60, que son vistas por la sociedad como personas convencionales, pero cuyas vidas íntimas resultan moralmente cuestionables. .
Ulisses has failed in his professional life, but leads a happy life with his wife Ângela and their two daughters. Until the day he is introduced to Bárbara, a very beautiful woman living in Rio de Janeiro. Ângela becomes her friend and gives her the dress Ulisses had given her. From then on, marital problems arise, and he becomes increasingly attracted to Bárbara.