Based on the novel Francisco by Anselmo Suárez y Romero, "The Other Francisco" is a socio-economic analysis of slavery and class struggle through the retelling of the original novel. The film contrasts the romantic conceptions of plantation life found in Suárez Romero's novel with a realistic expose of the actual historical conditions of slavery throughout the Americas. It offers a critical analysis of the novel, showing how the author's social background led to his use of particular dramatic structures to convey his liberal, humanitarian viewpoint.
Luis Aguilar, un artista mexicano, viaja a Cuba para filmar una película en compañía de la actriz y vedette Rosa Fornés. Todo se complica cuando su publicista inventa un romance entre ellos para darle publicidad a su película.