La querida banda de los Guardianes se instala en Knowhere. Pero sus vidas no tardan en verse alteradas por los ecos del turbulento pasado de Rocket. Peter Quill, aún conmocionado por la pérdida de Gamora, debe reunir a su equipo en una peligrosa misión para salvar la vida de Rocket, una misión que, si no se completa con éxito, podría muy posiblemente conducir al final de los Guardianes tal y como los conocemos.
Mientras Scott Lang se convierte en un súper héroe y en un padre, Hope van Dyne y el Dr. Hank Pym presentan una nueva misión urgente que encuentra a Ant-Man luchando junto a The Wasp para descubrir secretos de su pasado.
Un grupo de 83 americanos expatriados que trabajan en un edificio de Sao Paulo, Brasil, se ven atrapados en su lugar de trabajo mientras una voz les hace plantearse dudas morales sobre qué hacer en situaciones límites.
Young professionals Christopher and Melissa meet and fall hard for each other. As their attraction grows, it becomes apparent that in order for their relationship to succeed, they must overcome Christopher's dark secret involving his father, with the help of his best friend and a sharp-edged psychiatrist.
Schuyler and Osbourne Crawl must resolve a curse that was put on their father for his part in the slaughter of a Native-American village. The curse, invoked by a woman their father would only refer to as Black Eyed Sue, can only be broken if one of the two sons sacrifices himself. Taking their father's word to heart, they naively set out to undertake this grisly task.
After returning to her home-planet Pandora, infamous outlaw, Lilith, is given a dangerous mission and forms an alliance (and potential friendship) with other criminals; including former mercenary Roland, demolitionst Tiny Tina and her protector Krieg, insane scientist Tannis, and the wisecracking robot Claptrap. The mission: find and protect the missing (and important) daughter of a very powerful man named Atlas. Although, things may not be as they seem, as the girl holds the key to great power, one that can change the fate of the entire universe.
