1960. Night. A train on its way to the Iron Curtain. In it Sebastian - a guy like you and me. His actual mission was to escort an important painting to Prague. But after finding one of the guards murdered on the toilet, he is already in the middle of a bizarre 1960ies spy story.
Aurélie, propietaria de un pequeño restaurante en París, destrozada porque su novio le acaba de abandonar, encuentra por casualidad un libro, La sonrisa de las mujeres, que no sólo le salva la vida, sino que... cuenta su propia vida.