Personajes muy variopintos emprenden un largo, duro y peligroso viaje en diligencia. Entre ellos, un fuera de la ley en busca de venganza, una prostituta a la que han echado del pueblo, un jugador, un médico, la mujer embarazada de un militar y un sheriff. Las relaciones entre ellos serán difíciles y tensas. Además, durante el viaje, tendrán que afrontar el ataque de una partida de indios apaches.
Shirley Martin finds that Weylan has diverted the water from the valley and her cattle are dying. First she and her foreman Bob Lawson go to court. This fails when Weylan's men keep the ranchers from testifying. But Shirley has a second plan to return water to the valley.
When Montana cowpuncher Larry Benson, riding his horse Starlight and accompanied by his dog Rex, tied up at the hitching post in front of McAvoy's hotel in Dam, Texas, he had little idea of the extraordinary series of adventures that were in store for him, Starlight and Rex.
Yak arrives at the Gilmore ranch where rustling has occurred. Gilmore blames a wild horse when it is actually his foreman Mays. After Yak catches and tames the wild horse, Mays gets Yak out of the way by having him arrested for murder. Mays and his men can now make one last raid.
Carter Brace is out to murder Belden. Collins who was sent to bring in the border gang led by Brace, saves Belden's life in San Francisco. When they all reach the border, Brace tries again.
Eddie Manning, on a secret mission in Central America, is apparently penniless, and he becomes friends with a street urchin named Muggsy. When Muggsy is knocked down by a car, Manning meets its owner, Miriam Folansbee, and she offers him a job as a chauffeur. There is a plot to overthrow the country and Inez, a dancer at a cafe, tells Manning that Carlos Medina is the leader of the revolutionaries.