Un senador de los Estados Unidos desaparece en un laboratorio médico de Nuevo Méjico tras sufrir un grave accidente de coche. Sus heridas son completamente curadas por una organización secreta que ha desarrollado una tecnología médica muy avanzada. ¿Qué puede querer la organización a cambio de salvarle la vida? Mientras tanto, un periodista que ha presenciado el accidente decide investigar la desaparición del senador.
Lt. Col. George Armstrong Custer has been reinstated and assigned to command the 7th Cavalry Regiment at Fort Hays. The regiment has become a ragtag outfit of thieves and ruffians and Custer must whip the soldiers into shape to fight, the Kiowa, Sioux and Blackfoot tribes who confront them. These tribes are being supplied shotguns by a white gunrunner and Custer and his men must rescue General Terry and the Fifth Cavalry Regiment from annihilation when they are ambushed and trapped by a large Kiowa war party.
