Crippled as a young girl, Sabine vows to become a nun if cured. But when it turns out the original diagnosis was faulty and she regains the use of her legs, she decides to marry instead. Wreaked with guild when her first child is stillborn, Sabine enters a monastery where her sister Gertrude also resides. But after her sister dies of an illness, Sabine leaves the nuns behind and travels to India seeking peace.
After her mother -- a prostitute -- is murdered by her father, Sien is raised by her grandparents. Instead of a bourgeois life with grocer's son Gerrit van Buren, she chooses for an adventurous life with toutman Jan Meier. She follows him and becomes a revue artist in an Amsterdam cabaret, until her father comes to see her...
Greet y Nel, dos atípicas prostitutas que viven y trabajan juntas en el Barrio Rojo de Amsterdan, ofrecen "servicios especiales" a sus clientes. Mientras que Nel es esclavizada por su jefe y novio, Greta se enamora de Piet, el cual está casado.