UFC on ESPN: Whittaker vs. Gastelum (también conocido como UFC on ESPN 22 y UFC Vegas 24) fue un evento de artes marciales mixtas producido por el Ultimate Fighting Championship que tuvo lugar el 17 de abril de 2021 en las instalaciones del UFC Apex en Enterprise, Nevada, parte del área metropolitana de Las Vegas, Estados Unidos.
205 lbs.: Jan Blachowicz vs. Ronaldo Souza | 205 lbs.: Mauricio Rua vs. Paul Craig | 155 lbs.: Jared Gordon vs. Charles Oliveira | 185 lbs.: Antonio Arroyo vs. Andre Muniz | 185 lbs.: Markus Perez vs. Wellington Turman
Invicta FC 34: Porto vs. Gonzalez is mixed martial arts event headlined by a fight between Vanessa Porto and Pearl Gonzalez for the vacant Invicta FC Flyweight Championship. The event also featured the beginning of a flyweight tournament to determine the next number one contender.
Invicta FC 28: Mizuki vs. Jandiroba was a mixed martial arts event headlined by Mizuki Inoue vs. Virna Jandiroba fighting for the vacant strawweight championship. The event was originally scheduled to feature Virna Jandiroba vs. Janaisa Morandin for the title but Morandin pulled out of the fight on March 2. Mizuki was initially set to face Milana Dudieva before stepping in to replace Morandin in the main event. As a result, Dudieva was matched against Christina Marks.
Invicta FC 25: Kunitskaya vs. Pa'aluhi was a mixed martial arts event headlined by a fight between Yana Kunitskaya and Raquel Pa'aluhi for the vacated bantamweight championship. The co-main event was originally scheduled to be Lívia Renata Souza facing Jodie Esquibel for the vacated strawweight championship but Esquibel pulled out due to injury. Esquibel was replaced by Janaisa Morandin and the fight was then changed to a non-title bout. Amberlynn Orr was set to face Kelly McGill-Velasco but Kelly accepted a fight with the UFC and was replaced by newcomer Sarah Kleczka. Yaya Rincón was set to face Stephanie Egger but Egger withdrew and was replaced by Courtney King.