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George (Richard Gere) es un hombre en plena decadencia personal que se ve obligado a acudir a un refugio para los "sin techo" en Nueva York. Allí, sin recursos de ningún tipo y forzado a pedir en la calle, deberá enfrentarse a su nueva situación con la ayuda de Dixon, un veterano que le ayuda a retomar la relación con su hija Maggie, con la que perdió el contacto hace mucho tiempo.
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Dr. Anna Fugazzi is a young, attractive psychologist with a loving and devoted (albeit freakish) boyfriend, plenty of stimulating friends, and a bright future ahead of her. But beneath her perfect life and calm exterior lies a deadly secret that she herself cannot imagine, much less confront!!! There is a delicate balance between reality and illusion, between conscious and the subconscious, and for Dr. Fugazzi, the truth lies somewhere in between the beauty of her present life and the horror of the not-too-distant past!!! Shocked by hallucinations and deadly images, tantalized by familiar, eerie voices, provoked by her deranged and knowing patients, and daily nightmares that awaken her in a strange, white room, Dr. Fugazzi takes an inhuman journey into her very psyche!!!!