Set ten years after the finale's quintuple wedding, the special portrays the happily reunited San Román family, including four new grandchildren, as well as the Xochimilco residents. The San Románs go to Patricia's lake cabin in order to celebrate their shared ten-year wedding anniversary, unaware that Demetrio, whom they believe died after escaping from prison a year prior, is actually alive and well and is conspiring with his grandson, Ángel and Alma's young son Angelito, and the San Román grandchildren's nanny, Diana, to kill the entire family.
A few years pass after Paulina Martinez gets married to Carlos Daniel. She has two loving step-children and a new child of her own with Carlos Daniel. Everything seems like a happy end to the original story. But, when Paulina goes to the doctor to check up on an exam, only the worst happens, she thinks she has anemia, but the doctor has discovered that she has cancer and has only 6 months to live, now she must hide her secret from her husband, his children and her new baby.