In a Naples suspended between magic and superstition, madness and rationality, a mystery envelops the existence of Adriana (Giovanna Mezzogiorno), overwhelmed by a sudden love and a violent crime.
About the misadventures of Desidero, a pretty young Neapolitan transexual, and of his group of transvestite friends. Disappointed in love and politics, they set up an organic farm and psychological help centre for men in crisis.
Reclusive middle-aged male nurse Mauro may be in over his head when -- to save his hospital job -- he agrees to accompany 10-year-old illegal immigrant Eddi to meet his adoptive parents at the Swiss border. Along for the ride is a laconic small-time mobster named Rollo, and problems soon ensue in the form of car trouble, a Bulgarian hooker and her pimps.
Peppino is an aging taxidermist constantly ridiculed for being short and somewhat creepy. He meets Valerio, a handsome young man fascinated by Peppino's work. Peppino, in turn, becomes entranced by Valerio and offers him a large salary to come work as his assistant. But when Valerio meets Deborah, their fledgling romance is threatened by an insanely jealous third wheel.