Sue Pierce

Abby is a sought after massage therapist and a free spirit, while her brother Paul thrives on routine, running a failing dental practice with his assistant and daughter Jenny. Suddenly, Abby develops an aversion to bodily contact, which not only makes her unable to do her job, but also severely affects her relationship with her boyfriend. As Abby navigates her way through an identity crisis, her brother's dental practice receives new life when clients seek out his “healing touch.”

2日後に結婚する男性ダグは独身最後の夜を楽しもうと、悪友のフィルやステュ、これから義理の弟になるアランと、車でラスベガス旅行へ。ホテルのスイートルームに泊まり、一晩中ドンチャン騒ぎを続けた一行だが、翌朝目覚めるとダグの姿が見当たらない上、ホテルの室内は異様な光景に。フィルたちはダグが結婚式に間に合うよう彼を捜すが、自分たちの足跡をたどるうち、自分たちが一晩、いかにハメを外し過ぎたかを知っていく。