In a godforsaken bar in the middle of nowhere, an all-girl band – Ms. 45 – rips the stage apart with their punk spirit. But their performance impresses an enthusiastic fan who lures the girls into a trap, sedates them, and starts…customizing them. Slowly they begin to gain consciousness and, in total shock, realize their arms have all been replaced with axes and chainsaws to fight gladiator-style in a junkyard arena owned by a sadistic "emperor," forcing them into the battle of their lives with one prize in mind – their freedom.
When a woman is murdered, and her fiancé is the prime suspect, successful matchmaker Angie works to prove her client's innocence, much to the dismay of Kyle, the detective working the case.
A young boy finds a powerful otherworldly weapon, which he uses to save his older adoptive brother from a crew of thugs. Before long, the two of them are also pursued by federal agents and mysterious mercenaries aiming to reclaim their asset.