Set in rustbelt Buffalo circa 1980, Queen City follows the gritty struggle of two flawed detectives from both sides of the tracks whose private and public lives cross as they cope with strain in search of redemption and forgiveness.
After a man gets out of prison, he decides to go straight and leave his life of crime behind him. However, when he gets home he finds that his brother is in danger and the family farm is in foreclosure. He plans to take revenge on those responsible, but finds that he may have taken on more than he can handle.
The saga picks up in Washington, DC where Jian-wa is competing in a classical music competition. Back in LA, Jian-wa's brother Wago is wanted by the F.B.I. and manage to pull Jian-wa back to L.A. for questioning. They also want him to infiltrate his brother's gang in order to save his Wago. Can Jian-wa get Wago to see the truth about things before it's too late?
Maya, a New York artist and model, meets Joe, a drifter. They begin a passionate affair. On an impromptu trip to visit Joe's sister in the country, Joe's inner demons begin to surface.
As they enter their third year of medical school, a group of young students must prepare to decide what they intend to specialize in. Somehow, they must impress the Chief of Surgery while learning how to survive the life-and-death area of medicine and the complexity of their everyday lives.