It unfolds over eight days of sleep-deprived chaos and follows Jack, a down-on-his-luck fitness expert living with his mother in Los Angeles, who takes a maniacal swing at fame and fortune, trying to realize his version of the American dream.
Having just been through a tumultuous breakup, cam-girl Vicky retreats to a friend’s remote cabin in the woods to clear her head. But when the power goes out, she discovers something terrifying awaiting her in the dark — a masked killer who’s hellbent on bringing her night to a grisly end.
On May 30th, 2020, Uber and delivery driver Caddy searches for his missing son who has been living on the Los Angeles streets during the early days of the pandemic. Along the way, his path crosses that of Harry, a cult leader who is holding a bizarre ceremony up on Mulholland Drive. All the while, news of the horrific murder of George Floyd reverberates around the city and the social fabric collapses.
Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.