In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.
A drifter finds himself wrongly accused of murder by a power-crazed sheriff. The sheriff gives him a horse, some supplies, and a one-hour head start into the desert before sending his murderous posse after him.
A young woman arrives in New York City determined to become a great theatrical star, but discovers that her goal may not be as easily attainable as she had hoped.
When the temperamental star of a new Broadway musical revue in rehearsals walks out, director and choreographer Ted Sturgis suggests casting an unknown for the role. When it is announced in the newspapers, throngs of hopefuls show up. The revue's musical composer, Leo Belney, champions ballerina Joanna Moss, while gofer Bob Dowdy is enchanted by novice Suzy Doolittle. Then producer Felix Jordan persuades Ted's former dance partner, Madelyn Corlan, to come out of retirement to try out, much to Ted's great discomfort.
Howard Kemp has been tracking killer Ben Vandergroat for a long time. In the Colorado Rockies, he teams up with prospector Jesse Tate and former Union soldier Roy Anderson. Thinking Kemp is a sheriff, they agree to help for a small fee. When they catch Vandergroat, he tells them Kemp is pursuing a $5,000 bounty. After demanding equal shares, the uneasy alliance heads for Kansas as Vandergroat tries to turn them against each other.
Arriving at Medicine Bow, eastern schoolteacher Molly Woods meets two cowboys, irresponsible Steve and the "Virginian," who gets off on the wrong foot with her. To add to his troubles, the Virginian finds that his old pal Steve is mixed up with black-hatted Trampas and his rustlers...then finds himself at the head of a posse after said rustlers; and Molly hates the violent side of frontier life.