Shelby is devastated after her father's death. Curious about her family connections, she decides to look up the DNA-based family tree, and is surprised to find out that her father had another daughter. She goes on a mission to find her sibling and meets Rose, her half-sister. But as the initial euphoria dies down and the question of who gets her father's inheritance crops up, things begin to change.
In the waning months of World War II, a man and his wife are mistakenly identified as Jews by their anti-Semitic Brooklyn neighbors. Suddenly the victims of religious and racial persecution, they find themselves aligned with a local Jewish immigrant in a struggle for dignity and survival.
Married couples, unable to conceive, are thrilled to find they are going to become parents, thanks to a larger-than-life "miracle doctor" and his unusual treatments.
When plans with her boyfriend fall through, high school senior Chris Parker ends up babysitting the Anderson kids, Brad and Sara. What should be a quiet night in, however, turns into a series of ridiculous exploits, starting when they leave the house to pick up Chris' friend Brenda. Soon, Brad's buddy Daryl is involved, and the group must contend with car thieves, blues musicians and much more.