Earl Montgomery, a bombastic police academy reject, and Hank Rafferty, a disgraced, mild-mannered cop, can't seem to escape each other. They met on opposite sides of the law during a routine traffic stop that escalated out of control; now as lowly security guards they're thrown together to bust a smuggling operation.
After a comet disrupts the rain cycle of Earth, the planet has become a desolate, barren desert by the year 2033. With resources scarce, Kesslee — head of the powerful and evil Water & Power Corporation, the de facto government — has taken control of the water supply. Unwilling to cower under Kesslee's tyrannical rule, a pair of outlaws known as Tank Girl and Jet Girl rise up, joining the mysterious rebel Rippers to destroy the corrupt system.