Veteran Detective Ed Delopre and partner Mike McGivern have their hands full when they hit the pavement in search of a dangerous killer with five dead bodies already on his record. The mayor, in a rush to see peace restored in her city, makes a deal with the mob instead of waiting for Delopre and McGivern's results. Now that both sides of the law are involved in the killer's capture, the city is turned upside down.
Mary Lou, the prom queen burned to death by her boyfriend back in the fifties, has escaped from hell and is once again walking the hallways of Hamilton High School, looking for blood. She chooses as her escort in world of the living Alex, an average depressed student with dreams of one day becoming a doctor. As Mary Lou begins to get back into form, the body count starts climbing and the graduating class of Hamilton High is once again smaller than expected.