Raul, a Puerto Rican born in New York, meets Maria, a young Puerto Rican woman visiting NY, one night. Struck by love at first sight, he travels to Puerto Rico in search of this beautiful girl.
Roberta is a bored suburban housewife who is fascinated with a woman, Susan, she only knows about by reading messages to and from her in the personals section of the newspaper. This fascination reaches a peak when an ad with the headline "Desperately Seeking Susan" proposes a rendezvous. Roberta goes too, and in a series of events involving amnesia and mistaken identity, steps into Susan's life.
After several years of dreaming about the beautiful girl in a calendar photo, a composer, being overwhelmed by his girlfriend's jealousy, discovers that his next-door neighbor is that girl.