George
In a café in Marseille, a man's life begins to unravel when his lunch is disturbed by a chatty stranger. Something long forgotten has become dislodged in the darkness and is bubbling up towards the surface.
Ensler (uncredited)
前作での出来事の後、ゾーイとベンはエスケープ・ルームを仕掛けた企業、ミノス社を打倒すべく行動を開始した。ところが、2人はその過程で再びトラップだらけの部屋に閉じ込められてしまう。不可解なことに、その部屋にはかつてエスケープ・ルームから生還した人々（レイチェル、ブリアナ、ネイサン、テオ）が勢ぞろいしていた。ミノスの目的が分からないまま、ゾーイたちは生き残るために必死で知恵を絞っていくが、その果てにたどり着いたのは何とも悲しく、恐ろしい真実であった。
Patrick
Things turn sour when an amateur improv class meet for the first time after one of the group misjudges the situation.
Theo
Nearing her final year of Art college, Cassie faces the unwelcome onset of a rare neurological condition which leaves the hand she uses to paint, with a mind of its own.
Pike
Bambi drives her very pregnant best-friend Al to hospital to have her baby. They've decided that she's not going to keep it. Al's mood darkens as the inevitable and irreversible reality sinks in.
