Invicta FC 21: Anderson vs. Tweet was a mixed martial arts event that will be headlined by a bout between top featherweight contenders Megan Anderson and Charmaine Tweet competing for the interim featherweight championship. The event was scheduled to feature the MMA debut of undefeated professional boxer Heather Hardy against Brieta Carpenter, however Carpenter pulled out due to injury and the fight was removed from the card. A fight between Leah Letson and former UFC fighter Elizabeth Phillips was added instead. DeAnna Bennett was scheduled to fight Jodie Esquibel but pulled out of the fight and was replaced by Kali Robbins. Esquibel was then set to fight Robbins at a catchweight of 120 lbs but Robbins missed weight and the fight was canceled.
Invicta FC 12: Kankaanpää vs. Souza was a mixed martial-arts event headlined by Katja Kankaanpää defending her strawweight championship against Livia Renata Souza. Sijara Eubanks was scheduled to fight Roma Pawelek but Pawlek pulled out due to injury the week of the event and was replaced by Gina Begley. A fight between Cassie Rodish and Stephanie Skinner was originally scheduled but Skinner suffered an injury on the week of the show and the fight was pulled from the event.
Invicta FC 9 was headlined by Barb Honchak defending her flyweight championship against Takayo Hashi. The co-main event was be Mizuki Inoue against Karolina Kowalkiewicz.