Day in, day out, Niklas ‘Nick’ Tschiller and his partner Yalcin Gümer investigate crimes that are happening in Hamburg. But at some point even the policeman needs a break to spend time with his daughter Lenny. Then it says: Tschiller a.D. - out of service - goodbye to Hamburg. However, simply relaxing is easier said than done, because crime never sleeps and a new, very personal case throws a spanner in the works for Nick's plans for a well-deserved break. Even on vacation, the criminal investigator is not sure about his job and so a wild journey soon takes him across Europe, including to Istanbul and Moscow.
Ziege, Häschen and Max have now moved to Berlin for studying. They ain't got no money till the mystic plant reappears. Soon they have enough money for champagne, a penthouse and a nice car. But everyone's got private problems. Häschens girlfriend Valerie is in Sevilla, Max is too shy to go into Berlin's gay-clubs and Ziege is in love with the girlfriend of a manager of a big company. But being very boyish they don't just sell the SexUp pills, but also use them for themselves. Of course the old problems reappear.
Three best friends accidentally discover a tropical plant which is actually all-powerful aphrodisiac.The effects of this plant’s juices are amazing: people end up making passionate love with a first person they see and all the brakes cut loose instantly!
Flo is not quite a normal teenager: While all his friends only think about sex he can't even pronounce the word "S - E - X". But everything changes completely when one morning Flo wakes up from a strange call. His penis, excited for the first time, begins to talk to him. He claims that Flo severely neglected him for 15 years and it's time to release him.