타고난 바람둥이 제이미(제이크 질렌할 분)는 넘치는 바람기 때문에 다니던 직장에서 해고를 당한다. 제약회사에 영업사원으로 취직한 제이미는 자신의 매력을 100% 활용, 병원을 상대로 영업에 나선다. 얽매이길 싫어하는 자유로운 영혼의 소유자인 매기(앤 헤서웨이 분). 그녀는 진지한 사랑에 빠지길 두려워하며 가벼운 관계만을 쫓아 하룻밤 상대로 남자들을 고른다. 병원에 영업차 갔던 제이미는 그곳에서 환자인 매기를 우연히 만나게 되고 장난스럽고 유쾌한 제이미의 연애신청이 싫지 않은 매기는 진지한 사랑보다는 몇 시간을 함께 보낼 잠자리 친구로 지내자고 제안한다. 한편, 화이자가 개발한 비아그라가 선풍적인 인기를 끌면서 제이미는 업계에서 승승장구하게 된다. 몸으로 하는 사랑(?)엔 쿨하고 마음으로 하는 사랑은 싫은 두 사람은 시간이 지날수록 서로의 매력에 이끌리게 되고 제이미는 매기에게 사랑을 고백하지만 그녀는 받아들이지 않는데……
Action Reaction - when a Russian patron collapses at the bar, poison is suspected and Vittoria closes them down until the source is found.
After finish his work Marchino finds the body of a teenager girl and goes to BarLume to call the police who don't believe him after his infamous past. Massimo goes to check and here starts a new story of BarLume.
The King of Games - when a car accident results in death, the uncles suspect fowl play and want to investigate. Massimo is asked by the detective covering the case to keep a watch on the uncles and prevent them from interfering in the investigation.Tiziana, Massimo's server, is having second thoughts about her upcoming marriage. Massimo figues it out and shares his theory with the Detective.
Sea Air - Massimo seeks help for his nightmares and depression. The uncles have it in for a blind choir conductor. Tizi find a dead body, which leads to Massimo and Vittoria, who wants her old job back.
The Wild Boar Lodge - when a stag party ends with a murder Massimo finds himself the prime suspect.
Chinese Whispers - a dead psychic is found in the trunk of a car and the uncles find briefcase full of dough ($).
An English teacher brings soccer to a German school in the 19th Century.
An isolated villa, a family just like the others. Michele has remarried beautiful Damiana, and lives with her and her daughter Fiore, a seductive teen with whom he has an intricate relationship. In the middle of the night, Sergio, an ex-con, bursts in the villa and abducts the family. his mission: retrieve and bring back to Caligola, the man who hired him, some important documents, now seeminlgy buried somewhere in the greenhouse near the house.
Antonio and Emma have been separated for years, but he does not accept when Emma dates other men. Indeed Antonio proves obsessive, aggressive and intrusive, and again threatens Emma to hurt the children: little Kevin, shy and introverted, and the adolescent Valentina.
Song writer Mark Devereaux accidentally calls millions of green Martians to invade Earth. No they aren't dangerous, just wise-cracking, intrusive, pain in neck, annoyances. No one can escape their distracting influence. It's up to Mark to figure out how they got here, and most importantly, how to get rid of them before they drive everyone crazy!