Otilia is both blessed with a body that is the epitome of feminine perfection and cursed by an ugly mole that mars her beautiful face. The juxtaposition between fabulous beauty and disfigurement proves unsettling for the villagers and she grows up friendless, save the family's hired hand Melquíades. Though most figured she would end up as a prostitute, she is married off to Isidro, the local police chief. Cruel and petty, this ogre of a man brutalizes her and eventually infects her with venereal disease, rendering her sterile. With the help of Melquíades, Otilia takes a series of lovers to spite her husband. One day, the wounded Ruben -- a wanted outlaw -- staggers onto her doorstep and immediately she is in love. Much to Melquíades' chagrin, she harbors and tends to the criminal as her husband is out hunting for him.
The Driver is drafted by the UN to rescue a wounded war photographer named Harvey Jacobs from out of hostile territory. While they are leaving Jacobs tells the Driver about the horrors he saw as a photographer, but he regrets his inability to help war victims. Jacobs answers the driver curiosity about why he is a photographer by saying how his mother taught him to see. He gives the Driver the film needed for a New York Times story and also his dog tags to give to his mother. When they reach the border, they are confronted by a guard who begins to draw arms as Jacobs begins taking pictures, trying to get himself killed. The Driver drives through a hail of gunfire to the border, but finds Jacobs killed by a bullet through the seat. The Driver arrives in America to visit Jacobs' mother and share the news of him winning the Pulitzer prize and hand over the dog tags, only to discover that she is blind.