During the last moments of a romantic involvement with an older man, Martina finds herself deeply overwhelmed by disappointment and confusion, left alone to question who she really is.
On a gloomy Sunday in Mexico City, three friends in their twenties look for a female friend that disappears at an after-party. As they believe the worse could be happening, and while confronting characters and situations that represent a fraction of the problems of contemporary Mexico, their dreams, concerns and fears come to light.
Two longtime friends decide to attempt the Guadalupe Reyes challenge, which consist of drinking everyday from December the 12th (Day of Our Lady of Guadalupe) until January the 6th (Epiphany Day, the Feast of The Three Kings).
Minerva, a single mother, works long hours a day to keep her ailing daughter in the hospital. One day, a mysterious man arrives at her door offering her to work in the translation of an ancient book in exchange for a substantial sum of money. Minerva accepts without knowing that this will change her life and that of those around her forever.
In a cozy bistro, an increasingly heated discussion between two good buddies reveals their latent sexual prejudices, as one admits to feeling finally set free by a book he has just read.
Dante travels to Lagos de Moreno to see an old girlfriend who is about to marry. By chance he meets an Italian tourist named Domenica and they spend the night wandering through the city streets. Among memories of lost loves, Dante and Domenica eventually discover they are soul mates.