On the day of his first communion, the boy Honorato is orphaned because the mafia murders his parents. Before dying, the father recommends that the son defend himself against whoever tries to harm him, so that over time he becomes a bloodthirsty and sadistic gunman, always accompanied by the ghost of his father. His fame bears in the ears of Rutilo, the boss of the central supply, who hires him to avenge the death of his son. Honorato fulfills the mission with luxury of violence and becomes a trusted man of the gangster.
Over more than thirty years, a department of the Condesa in Mexico City, is the setting in which they are carried out ten stories, mixed, form one whose only constant is the rupture. The passage of time and the outside world only guess through the windows and objects that come with the characters. The set is a great solitude, possible in a city of the blind.
A beautiful woman is abandoned by her husband during their honeymoon, she stays alone in the hotel where she meets other guests and listen to their stories.
Tomás Tomás is a young yuppie playboy with a string of discarded girlfriends. But when Silvia, the victim of one of his adventures, tries to get revenge by typing "positive" on his AIDS test, Tomás experiences for the first time the realities of love and death.
