"Little Boy Big Boy" tells the story of a carefree graphic artist named Raymund and how he is filled with doubt as he is suddenly faced with the responsibility of looking after his seven-year-old nephew Zach. But while taking care of Zach, Raymund finds himself in the middle of building a relationship with his new lover Tim where he teaches him the value of acceptance and self-respect.
After experiencing heartache, Adrian a.k.a. Ada - a conservative homosexual, leaves the city with his cousin Aruba. Relocating to a quaint province to start a new life and a parlor business, she meets her assistant Didi, her new secret love Dodong and a multitude of wacky characters including Dodong's brother Poldo, the peculiar couple Aling Britney and Mang Justin and her arch-rival when it comes to Dodong's affections Krystal. When a mysterious stone engraved with the words "Zaturnnah" falls from the sky one night, Ada gulps it down and he is magically transformed into Zsa Zsa Zaturnnah, a super heroine with immense strength and extraordinary beauty. In the pursuit of liberty, truth, justice and loads of excellent hair coloring, she fearlessly defends her newfound home from a giant frog, zombies running amok and from the overbearing Amazonistas from Planet X led by man-hater Queen Femina.
Talkative Lianne and colorful gay Osmond become fast friends when they meet at the first Gay Pride Parade in Malate in the early 80's. For the next thirty-plus years of their lives, they'll do everything together, whether it's eating, shopping, discussing life and even looking for the perfect man! So inseparable are their pair that even their mothers become best friends too.
Three advertising executives are doomed to perpetually look for the right man. Tates, Katie and Sonia are all are stuck in a rut with love, sex and marriage. Tates will do whatever it takes to just to have the man she wants even if he is tangled in a messy annulment case and even if it takes her to shed a lot of money to have him. Katie found her love story with a macho dancer but is scared to let her friends know because of his unconventional job. So she tries to give him a more decent look for her friends to see. She also finds bodily insecurities because of her chubby physique. Sonia is the two-timing chick that finds her self pregnant while being with two men. She is in-love with a painter but finds more security with a rich man. Despite her strong feelings for the former, she chooses to be with the latter in order to provide better for her and her child.