Garage owner Angelo and big-time film producer Alberto find themselves occupying neighbouring beds in a Rome hospital after suffering heart attacks. Alberto is a gregarious joker - and chain smoker - who has a strong effect on the impressionable Angelo. However, as one of the men's condition deteriorates, the other becomes more deeply involved in his personal life.
After the death of her husband Fausto, Stella decides to return to the house by the lake where she was born and where twenty years earlier she knew him, remaining conquered by the melancholy.
In the Tuscan countryside at the end of the 19th century, Pietro, the shy son of a tyrannical landowner, falls in love with Ghisola, a peasant girl with no family. His father has her sent away. Years later, the two meet again: still in love with her, Pietro would like to marry her, but she has become the mistress of a married man.
An epileptic 12-year-old girl, Pippi, is hospitalized in the psychiatric ward instead of the neurological ward, due to an administration error. Out of this mistake begins the difficult journey towards being cured.