I 'Anja og Viktor – I medgang og modgang', den femte Anja og Viktor-film, er parret kommet i pengemangel. De bor sammen med deres lille datter i vennernes ramponerede øvelokale i Sydhavnen, men da kommunens ivrige mand afslører dem i at bruge øvelokalet som bolig, og de nu regulært står på gaden, hvis de ikke skaffer penge til lejligheden, er familien i en presset situation.
Finally, Viktor becomes a fireman, while Anja still do not have the great success of the advertising agency. Fortunately, they have each other and everything is bright as Anja gets a great opportunity at the office while being pregnant. Then Viktor just figure out how to be soft father, understanding man and tough firefighter at once. But how hard can it be?
Anja is a beautiful and very well proportioned high school senior... and still a virgin. She insists that she wants her first time to be with a guy, who knows what it's about. Her rich (and arrogant, pretentious and obnoxious) boyfriend Peter serves the purpose, and he's more than willing. In fact, he's pushing forward as much as he can, but Victor, a freshman who has a serious crush on Anja, has other plans. Her first time should definitely not be with this buffoon, and he's ready to take it VERY far!
12-year-old Martin finds the going tough. Manhood is approaching, but so far mostly as aches and pain. His mother's men friends are definitely nothing like the father he does not have. So some kind of male bonding is inevitable when he meets Funder, a juvenile droput on the run from the police. There is also girl-friend Rikke to consider. Who needs Martin the most? Coming of age isn't so easy.