In 1972, the patients and doctors at Stephens Sanitarium were brutally murdered. Over forty years later, the only known survivor returns only to find the ghosts of the past have not been resting in peace.
A controversial therapist assembles a group of discontented wives and prescribes using adultery to save their failing marriages, only to have her patients killed off one by one.
Thrown out of her home by a jealous husband, a woman sinks into degradation. Twenty years later, she is charged with killing a man bent on harming her daughter. The daughter, unaware of who the woman is, takes the assignment to defend her in court.
Newlyweds Helen and Paul go to a backwoods cabin on vacation. When Paul goes back to the car for some cigarettes he's not given a chance to ponder the carcinogenic ramifications as an axe blade makes the point moot. Panic stricken, Helen runs into the woods, only to find Odie Pickett as her only savior. He takes her back to his place, where pregnant wife Emmy, thick-as-a-brick son Bo, and available-since-she-was-twelve daughter Sarah, do their best to give her a "family" welcome. While Helen's immediate danger is somewhat delayed, her newfound shelter begins showing some signs of danger as well.